CD143A-SR70

CD143A-SR70 isn’t a widely recognized entry in major databases. It may be a lab-specific alias for a form or splice variant of ACE (CD143) or a study construct. If you mean ACE (CD143):
ACE (angiotensin-converting enzyme) is a zinc-dependent metallopeptidase that converts angiotensin I to angiotensin II and degrades vasodilators like bradykinin. The somatic ACE protein is a type I membrane glycoprotein with two catalytic domains (N- and C-); a shorter form (testis ACE) has a single domain. It exists as membrane-bound and soluble forms (the latter from ectodomain shedding). Expression is broad, notably in vascular endothelium, kidney, heart, and lungs. Functions include blood pressure regulation, electrolyte balance, and inflammatory modulation. Clinically, ACE inhibitors are used to treat hypertension, heart failure, and kidney disease. Detection methods include ACE activity assays and antibodies against CD143, as well as ACE mRNA analysis.
If SR70 refers to a specific splice variant or experimental construct, please share the context for a tailored introduction.

I’m not sure which vendor’s CD143A-SR70 you mean. Packaging varies by manufacturer. Please specify the vendor or share the datasheet/link; the exact package could be SOP-8, SO-8, TSSOP-8, QFN, etc.

CD143A-SR70 is a monoclonal antibody against ACE (CD143). Reported application areas include:
- Flow cytometry for cell-surface ACE
- Immunohistochemistry and immunocytochemistry on FFPE or frozen samples
- Western blot for ACE protein
- ELISA for ACE detection (sandwich format)
- Immunoprecipitation/pulldown assays
- Immunofluorescence staining